BAli-Phy: simultaneous Bayesian inference of alignment and phylogeny
نویسندگان
چکیده
SUMMARY BAli-Phy is a Bayesian posterior sampler that employs Markov chain Monte Carlo to explore the joint space of alignment and phylogeny given molecular sequence data. Simultaneous estimation eliminates bias toward inaccurate alignment guide-trees, employs more sophisticated substitution models during alignment and automatically utilizes information in shared insertion/deletions to help infer phylogenies. AVAILABILITY Software is available for download at http://www.biomath.ucla.edu/msuchard/bali-phy.
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عنوان ژورنال:
- Bioinformatics
دوره 22 16 شماره
صفحات -
تاریخ انتشار 2006